Showing posts with label Health. Show all posts
Showing posts with label Health. Show all posts

Biogen says Lou Gehrig’s disease drug fails in trial






(Reuters) – An experimental drug to combat amyotrophic lateral sclerosis, commonly called Lou Gehrig‘s disease in the United States, failed to work in an important trial and Biogen Idec said it would stop development of the treatment.


The drug, dexpramipexole, had shown promise and seemed to work against ALS in a mid-stage clinical trial in 2011.






Biogen shares fell 6 percent in premarket trading on Thursday.


ALS is a disease of nerve cells in the brain and spinal cord that affects about 30,000 Americans, according to the ALS Association. About 5,600 Americans are diagnosed with the disease each year. American baseball player Henry Louis “Lou” Gehrig died of the disease in 1941.


There is currently only one drug that is used to help people with ALS – Rilutek, or riluzole, made by Sanofi. It has been shown to prolong the life of people with ALS, who have a life expectancy of two to five years after diagnosis.


The news was an uncommon blow for a company that has excelled in recent years and could push shares down about 10 percent, Mark Schoenebaum, a biotech analyst at ISI Group, said in an early research note.


He said analysts had estimated sales for the drug in 2016 of about $ 350 million – or about 4 percent of Biogen revenue.


The late-stage dexpramipexole trial, which was called Empower and enrolled 943 people with ALS at 81 sites in 11 countries, did not show that the drug increased the ability of people with the disease to function or improved their survival rates.


“We share the disappointment of members of the ALS community, who had hoped that dexpramipexole would offer a meaningful new treatment option,” Biogen Executive Vice President of Research and Development Douglas Williams said in a statement.


The company said it would continue to work on potential treatments for the disease.


(Reporting by Caroline Humer in New York and Esha Dey in Bangalore; Editing by Roshni Menon, Nick Zieminski and John Wallace)


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Mandela’s recovery “on track” at home: South African government






JOHANNESBURG (Reuters) – Former South African President Nelson Mandela‘s recovery is ‘on track’ at his home in Johannesburg, the government said on Wednesday in its first statement since the anti-apartheid hero was released from hospital a week ago.


Mandela, 94, who has been in frail health for several years, spent nearly three weeks in a Pretoria hospital in December for treatment of a lung infection and surgery to remove gallstones, his longest stay for medical care since his release from prison in 1990.






“Madiba’s recovery continues on track,” presidency spokesman Mac Maharaj said referring to Mandela by his clan name.


“We are now in the phase where if we do not hear from his doctors, we assume he is all right,” he said, without giving details on Mandela’s condition.


Mandela has been receiving what the government calls “home-based high care” at his residence in an upscale Johannesburg neighborhood.


Mandela became South Africa‘s first black president after the first all-race elections in 1994, serving a five-year term.


He has been mostly absent from the political scene for the past several years due to poor health, while questions have been raised as to whether his ruling African National Congress (ANC) has lost the moral compass he left behind.


Under such leaders as Mandela, Walter Sisulu and Oliver Tambo, the ANC gained a stellar global reputation. Once the yoke of apartheid was thrown off, it began ruling South Africa in a blaze of goodwill from world leaders who viewed it as a beacon for a troubled continent and world.


Close to two decades later, this image has dimmed as critics inside and outside the country, and in the movement itself, accuse ANC leaders of indulging in the spoils of office, squandering mineral resources and engaging in power struggles.


Mandela’s “Rainbow Nation” of reconciliation has come under strain under President Jacob Zuma, a Zulu traditionalist with a history of racially charged comments, including a statement in December where he reportedly said dog ownership was for whites and not part of African culture.


Nobel Peace Prize laureate Mandela has a history of lung problems dating back to when he contracted tuberculosis as a political prisoner. He spent 27 years in prison, including 18 years on the windswept Robben Island off Cape Town.


Mandela was also admitted to hospital in February because of abdominal pain but released the following day after a keyhole examination showed there was nothing seriously wrong with him.


He has spent most of his time since then in another home in Qunu, his ancestral village in the impoverished Eastern Cape province.


His poor health has prevented him from making public appearances in the past two years, although he has continued to receive high-profile visitors, including former U.S. President Bill Clinton.


(Reporting by Jon Herskovitz; Editing by Janet Lawrence)


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Women Lose Half Their Weight: How They Did It






At 25 years old and 288 pounds, Ashley Donahoo was depressed.


“I was unhappy with my job, I was unhappy with the direction my life was going, and I had a hard time enjoying the little things that my kids wanted to do,” the 27-year-old mother of two from Pace, Fla., said. “My health was failing. My doctor told me that he didn’t think I was going to make it to 30 if I kept on [this way]. … It kept getting worse and worse.”






Donahoo was concerned, but it was her faithful husband, David, who pushed her on a path to health, starting with a walk around the block.


“His heart was breaking for me,” she said. “And he saw how unhappy I was, and he came to me and said, ‘We’re going to go for a walk.’  And I was, like, ‘No, we’re not.’”


Her husband won that battle, and on the walk, she started thinking about her own choices and future.


“The realization hit me that I made this choice.  I made this choice to get where I am right now.  So I’m going to start making a different choice,” she said.   ”I put my health and myself on back burner, and I think … it had all caught up to me.”


Jumpstart Your Weight Loss: CLICK HERE to Ask a Celebrity Trainer a Question!


Like Donahoo, Caroline Jhingory reached a similar eye-opening realization about her weight.


“I looked in the mirror one day and just realized I didn’t recognize the person that was staring back at me,” said Jhingory, 32, of Washington, D.C.


Jhingory’s struggles with her weight began early. At age 8, she weighed 120 pounds. Taunted by her peers, Jhingory was enrolled in a medical weight loss program, but it didn’t work because she would sneak junk food like candy bars.


“I found a way to be a food hustler and get whatever food I wanted,” she said. “Not only did I spend two decades of my life morbidly obese. I spent two decades of my life being taunted and teased in every environment. I never went to prom. I never had dates. I couldn’t ride a roller coaster because the safety bar wouldn’t go over my stomach.”


Jhingory remained heavy until college, when she tipped the scales at 303 pounds and started feeling self-conscious in her new environment.


“I felt like I had a moment when all these difficult experiences were a huge pause button on my life. I finally said to myself, ‘I’m tired of this. I want to have a normal life.’”


Jhingory started walking everywhere. Then, she took up a daily cardio regimen to shed the weight, and she rid her pantry of tempting snack foods she once binged on. Now 149 pounds, she has reclaimed her shape and kept off the weight.


Jhingory’s amazing transformation, along with Donahoo’s and other weight-loss success stories, were spotlighted in the “Half Their Size” feature in the latest issue of People magazine.


RELATED: Is Being Overweight Really Bad For You?


Donahoo cut out the late-night binges that brought her down and, thanks to her strong support system, lost 137 pounds. She credited her weight loss success to tracking her food and exercise on livestrong.com and running. She has run two 5Ks.


Leah Fernandez of Atlanta found herself at 251 pounds after two pregnancies. The baby weight stuck and she tended to eat emotionally.


“I wanted the food,” she said. “It made me feel good, and so I ate it.”


But it was the motivation to be there for her children that helped her turn it all around.


“Thinking about going out to the park with my kids felt like work to me, you know?  And at some point I realized that’s ridiculous. Not only am I cheating myself but I’m cheating my kids of me,” she said.


Fernandez turned to Jenny Craig in March 2011 and hasn’t looked back. Since then, she has lost half her weight by staying active with her kids and incorporating walking into her lifestyle.


“I’m getting my groove back.  Leah’s getting her groove back,” she said.


RELATED: Apps to Help With Weight-Loss Resolutions


RELATED: 329 Pound-Weight-Loss Trio Share Their Secrets


READ MORE: 138 Pound Weight Loss Changes Woman’s Life


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Omega-3s may not protect against faulty heart rhythm






NEW YORK (Reuters Health) – Sorry, Charlie, but fish oil supplements did not prevent atrial fibrillation in patients who had already experienced episodes of the heart rhythm malfunction, a new clinical trial has found.


The study, published in the Journal of the American College of Cardiology, adds to a growing pool of disappointing evidence regarding the protective effects of omega-3 fatty acids on heart health.






“The results for atrial fibrillation are important negative findings, answering key clinical and research questions,” said Dr. Dariush Mozaffarian, an omega-3 expert at the Harvard School of Public Health, who was not involved in the current study.


The new research, combined with other trials, “indicates that short-term fish oil use is unlikely to prevent recurrent atrial fibrillation,” he said.


But if the supplements don’t prevent heart rhythm problems, they don’t appear to be dangerous, either. “In all these studies, fish oil was safe and well-tolerated, with no evidence for increased bleeding,” Mozaffarian told Reuters Health.


Atrial fibrillation, in which the heart’s upper chambers beat out of step with those below, affects nearly one in 10 Americans in their 80s. The condition is linked to potentially life-threatening strokes and heart failure.


Although doctors prescribe certain medications to treat the condition, none to date has proven particularly effective. As a result, most drug treatment focuses on preventing strokes by administering blood thinners to dissolve clots caused by the fibrillation.


Some evidence suggests that omega-3 fatty acids, found in oily fish like sardines and tuna, might reduce the risk of atrial fibrillation, although exactly how they would produce their effect is not clear.


A study published earlier this year in Circulation, for example, found that people with the most omega-3s in their blood had a 30 percent lower chance of developing an irregular heart beat than those with the lowest concentrations of the substances (see Reuters Health story of February 1, 2012).


That 30 percent difference would work out to eight fewer cases of atrial fibrillation per 100 people – which would be a meaningful benefit if it could be enjoyed by those with fibrillation or at risk for it, just by consuming more omega 3s.


But the latest study suggests that it probably can’t. The trial included 586 men and women with a history of atrial fibrillation who were given a gram a day of fish oil or dummy capsules for a year. Participants also were allowed to take other drugs to control their heart rhythms, as prescribed by their doctors.


At the end of the study period, about 24 percent of the people who took fish oil, and 20 percent of those who did not, had experienced a recurrence of atrial fibrillation – a difference so small, statistically, it was likely due to chance.


The supplements also did not appear to reduce the risk of other cardiovascular ailments – including stroke, heart attack, heart failure – or death from any cause.


The findings on atrial fibrillation echo results from a study led by Mozaffarian published in November, of patients recovering from heart surgery.


Even so, Dr. Alejandro Macchia, a cardiologist at the GESICA Foundation in Buenos Aires, who led the current study and collaborated with Mozaffarian on the previous one, said fish oil may still prove beneficial for heart health, at least in some patients.


“I am not sure the story is over,” Dr. Macchia told Reuters Health. “I think we have enough evidence to say that there is no role of (omega-3 fatty acids) for the prevention of atrial fibrillation” in patients with a history of the condition, he said. “However in the context of primary prevention – those people who had never had a previous episode of atrial fibrillation – there is a reasonable room for a well-designed and very large clinical trial.”


SOURCE: http://bit.ly/VrTKiY Journal of the American College of Cardiology, online December 19, 2012.


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Clinton receiving blood thinners to dissolve clot






WASHINGTON (AP) — Doctors treating Secretary of State Hillary Rodham Clinton for a blood clot in her head said blood thinners are being used to dissolve the clot and they are confident she will make a full recovery.


Clinton didn’t suffer a stroke or neurological damage from the clot that formed after she suffered a concussion during a fainting spell at her home in early December, doctors said in a statement Monday.






Clinton, 65, was admitted to New York-Presbyterian Hospital on Sunday when the clot turned up on a follow-up exam on the concussion, Clinton spokesman Phillipe Reines said.


The clot is located in the vein in the space between the brain and the skull behind the right ear. She will be released once the medication dose for the blood thinners has been established, the doctors said.


In their statement, Dr. Lisa Bardack of the Mount Kisco Medical Group and Dr. Gigi El-Bayoumi of George Washington University said Clinton was making excellent progress and was in good spirits.


Clinton’s complication “certainly isn’t the most common thing to happen after a concussion” and is one of the few types of blood clots in the skull or head that are treated with blood thinners, said Dr. Larry Goldstein, a neurologist who is director of Duke University’s stroke center. He is not involved in Clinton’s care.


The area where Clinton’s clot developed is “a drainage channel, the equivalent of a big vein inside the skull. It’s how the blood gets back to the heart,” Goldstein said.


Blood thinners usually are enough to treat the clot and it should have no long-term consequences if her doctors are saying she has suffered no neurological damage from it, Goldstein said.


Clinton returned to the U.S. from a trip to Europe, then fell ill with a stomach virus in early December that left her severely dehydrated and forced her to cancel a trip to North Africa and the Middle East. Until then, she had canceled only two scheduled overseas trips, one to Europe after breaking her elbow in June 2009 and one to Asia after the February 2010 earthquake in Haiti.


Her condition worsened when she fainted, fell and suffered a concussion while at home alone in mid-December as she recovered from the virus. It was announced Dec. 13.


This isn’t the first time Clinton has suffered a blood clot. In 1998, midway through her husband’s second term as president, Clinton was in New York fundraising for the midterm elections when a swollen right foot led her doctor to diagnose a clot in her knee requiring immediate treatment.


Clinton had planned to step down as secretary of state at the beginning of President Barack Obama’s second term. Whether she will return to work before she resigns remained a question.


Democrats are privately if not publicly speculating: How might her illness affect a decision about running for president in 2016?


After decades in politics, Clinton says she plans to spend the next year resting. She has long insisted she had no intention of mounting a second campaign for the White House four years from now. But the door is not entirely closed, and she would almost certainly emerge as the Democrat to beat if she decided to give in to calls by Democratic fans and run again.


Her age — and thereby health — would probably be a factor under consideration, given that Clinton would be 69 when sworn in, if she were elected in 2016. That might become even more of an issue in the early jockeying for 2016 if what started as a bad stomach bug becomes a prolonged, public bout with more serious infirmity.


Not that Democrats are willing to talk openly about the political implications of a long illness, choosing to keep any discussions about her condition behind closed doors. Publicly, Democrats reject the notion that a blood clot could hinder her political prospects.


“Some of those concerns could be borderline sexist,” said Basil Smikle, a Democratic strategist who worked for Clinton when she was a senator. “Dick Cheney had significant heart problems when he was vice president, and people joked about it. He took the time he needed to get better, and it wasn’t a problem.”


It isn’t uncommon for presidential candidates’ health — and age — to be an issue. Both in 2000 and 2008, Sen. John McCain, R-Ariz., had to rebut concerns he was too old to be commander in chief or that his skin cancer could resurface.


Two decades after Clinton became the first lady, signs of her popularity — and her political strength — are ubiquitous.


Obama had barely declared victory in November when Democrats started zealously plugging Clinton as their strongest White House contender four years from now, should she choose to take that leap.


“Wouldn’t that be exciting?” House Democratic leader Nancy Pelosi declared in December. “I hope she goes. Why wouldn’t she?”


Even Republicans concede that were she to run, Clinton would be a force to be reckoned with.


“Trying to win that will be truly the Super Bowl,” Newt Gingrich, the former House Speaker and 2012 GOP presidential candidate, said in December. “The Republican Party today is incapable of competing at that level.”


Americans admire Clinton more than any other woman in the world, according to a Gallup poll released Monday — the 17th time in 20 years that Clinton has claimed that title. And a recent ABC News/Washington Post poll found that 57 percent of Americans would support Clinton as a candidate for president in 2016, with just 37 percent opposed. Websites have already cropped up hawking “Clinton 2016″ mugs and tote bags.


Beyond talk of future politics, Clinton’s three-week absence from the State Department has raised eyebrows among some conservative commentators who questioned the seriousness of her ailment after she canceled planned Dec. 20 testimony before Congress on the deadly attack on the U.S. diplomatic mission in Benghazi, Libya.


Clinton had been due to discuss with lawmakers a scathing report she had commissioned on the attack. It found serious failures of leadership and management in two State Department bureaus were to blame for insufficient security at the facility. Clinton took responsibility for the incident before the report was released, but she was not blamed. Four officials cited in the report have either resigned or been reassigned.


___


Associated Press writer Ken Thomas in Washington and AP Chief Medical Writer Marilynn Marchione in Milwaukee contributed to this report.


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FDA approves 1st new tuberculosis drug in 40 years






WASHINGTON (AP) — The Food and Drug Administration says it has approved a Johnson & Johnson tuberculosis drug that is the first new medicine to fight the deadly infection in more than four decades.


The agency approved J&J’s pill, Sirturo, for use with other older drugs to fight hard-to-treat tuberculosis.






Sirturo is the first medicine specifically designed for treating multi-drug-resistant tuberculosis. That’s an increasingly common form of the disease that cannot be treated with at least two of the four primary antibiotics used to treat tuberculosis.


The standard drugs used to fight the disease were developed in the 1950s and 1960s.


Roughly one-third of the world’s population is estimated to be infected with the bacteria causing tuberculosis.


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Vomiting Larry battles “Ferrari of the virus world”






LONDON (Reuters) – Poor Larry isn’t looking too good. He’s pale and clammy and he’s been projectile vomiting over and over again while his carers just stand by and watch.


Yet their lack of concern for Larry is made up for by their intense interest in how far splashes of his vomit can fly, and how effectively they evade attempts to clean them up.






Larry is a “humanoid simulated vomiting system” designed to help scientists analyze contagion. And like millions around the world right now, he’s struggling with norovirus – a disease one British expert describes as “the Ferrari of the virus world”.


“Norovirus is one of the most infectious viruses of man,” said Ian Goodfellow, a professor of virology at the department of pathology at Britain‘s University of Cambridge, who has been studying noroviruses for 10 years.


“It takes fewer than 20 virus particles to infect someone. So each droplet of vomit or gram of feces from an infected person can contain enough virus to infect more than 100,000 people.”


Norovirus is hitting hard this year – and earlier too.


In Britain so far this season, more than a million people are thought to have suffered the violent vomiting and diarrhea it can bring. The Health Protection Agency (HPA) said this high rate of infection relatively early in the winter mirrors trends seen in Japan and Europe.


“In Australia the norovirus season also peaks during the winter, but this season it has gone on longer than usual and they are seeing cases into their summer,” it said in a statement.


In the United States, the Centers for Disease Control and Prevention (CDC) say norovirus causes 21 million illnesses annually. Of those who get the virus, some 70,000 require hospitalization and around 800 die each year.


PROFUSE AND PROJECTILE


Norovirus dates back more than 40 years and takes its name from the U.S. city of Norwalk, Ohio, where there was an outbreak of acute gastroenteritis in school children in November 1968.


Symptoms include a sudden onset of vomiting, which can be projectile, and diarrhea, which may be profuse and watery. Some victims also suffer fevers, headaches and stomach cramps.


John Harris, an expert on the virus at Britain’s HPA, puts it simply: “Norovirus is very contagious and very unpleasant.”


What makes this such a formidable enemy is its ability to evade death from cleaning and to survive long periods outside a human host. Scientists have found norovirus can remain alive and well for 12 hours on hard surfaces and up to 12 days on contaminated fabrics such as carpets and upholstery. In still water, it can survive for months, maybe even years.


At the Health and Safety Laboratory in Derbyshire, northern England, where researcher Catherine Makison developed the humanoid simulated vomiting system and nicknamed him “Vomiting Larry”, scientists analyzing his reach found that small droplets of sick can spread over three meters.


“The dramatic nature of the vomiting episodes produces a lot of aerosolized vomit, much of which is invisible to the naked eye,” Goodfellow told Reuters.


Larry’s projections were easy to spot because he had been primed with a “vomitus substitute”, scientists explain, which included a fluorescent marker to help distinguish even small splashes – but they would not be at all easily visible under standard white hospital lighting.


Add the fact that norovirus is particularly resistant to normal household disinfectants and even alcohol hand gels, and it’s little wonder the sickness wreaks such havoc in hospitals, schools, nursing homes, cruise ships and hotels.


During the two weeks up to December 23, there were 70 hospital outbreaks of norovirus reported in Britain, and last week a cruise ship that sails between New York and Britain’s Southampton docked in the Caribbean with about 200 people on board suffering suspected norovirus.


MOVING TARGET


The good news, for some, is that not everyone appears to be equally susceptible to norovirus infection. According to Goodfellow, around 20 percent of Europeans have a mutation in a gene called FUT2 that makes them resistant.


For the rest the only likely good news will have to wait for the results of trials of a potential norovirus vaccine developed by U.S. drugmaker LigoCyte Pharmaceuticals Inc, or from one of several research teams around the world working on possible new antiviral drugs to treat the infection.


Early tests in 2011 indicated that around half of people vaccinated with the experimental shot, now owned by Japan’s Takeda Pharmaceutical Co, were protected from symptomatic norovirus infection.


The bad news, virologists say, is that the virus changes constantly, making it a moving target for drug developers. There is also evidence that humans’ immune response to infection is short-lived, so people can become re-infected by the same virus within just a year or two.


“There are many strains, and the virus changes very rapidly – it undergoes something virologists call genetic drift,” Harris said in a telephone interview. “When it makes copies of itself, it makes mistakes in those copies – so each time you encounter the virus you may be encountering a slightly different one.”


This means that even if a vaccine were to be fully developed – still a big ‘if’ – it would probably need to be tweaked and repeated in a slightly different formula each year to prevent people getting sick.


Until any effective drugs or vaccines are developed, experts reckon that like the common cold, norovirus will be an unwelcome guest for many winters to come. Their advice is to stay away from anyone with the virus, and use soap and water liberally.


“One of the reasons norovirus spreads so fast is that the majority of people don’t wash their hands for long enough,” said Goodfellow. “We’d suggest people count to 15 while washing their hands and ensure their hands are dried completely.”


(Reporting by Kate Kelland; Editing by Will Waterman)


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Republican Senator: chances for “fiscal cliff” deal “exceedingly good”






WASHINGTON (Reuters) – Republican Senator Lindsey Graham said on Sunday that chances for a small “fiscal Cliff” deal in the next 48 hours were “exceedingly good” and that President Barack Obama had won.


“I think people don’t want to go over the cliff if we can avoid it,” Graham said on Fox News Sunday.






“This deal won’t affect the debt situation, it will be a political victory for the president and I hope we’ll have the courage of our convictions when it comes time to raise the debt ceiling to fight for what we believe as Republicans, but hats off to the president, he won,” Graham said.


(Reporting By Tabassum Zakaria; Editing by David Brunnstrom)


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Obama says failure to reach fiscal deal would hurt markets






WASHINGTON (Reuters) – Financial markets would be affected adversely if U.S. lawmakers fail to agree on a “fiscal cliff” deal before Tuesday, President Barack Obama said in an interview broadcast on Sunday, while urging Congress to act quickly to extend tax cuts for middle-class Americans.


Lawmakers are seeking a last-minute deal that would set aside $ 600 billion in tax increases and across-the-board government spending cuts that are set to start within days. If Congress does not make that happen, the first bill brought up in the new year would be to reduce taxes for middle-income families, Obama told NBC’s “Meet the Press.”






“Now I think that over the next 48 hours, my hope is that people recognize that, regardless of partisan differences, our top priority has to be to make sure that taxes on middle-class families do not go up. That would hurt our economy badly,” Obama said in the interview taped on Saturday.


“We can get that done. Democrats and Republicans both say they don’t want taxes to go up on middle-class families. That’s something we all agree on. If we can get that done, that takes a big bite out of the ‘fiscal cliff.’ It avoids the worst outcomes,” Obama added.


Low income tax rates first put in place under Republican former President George W. Bush are due to expire at the end of the day on Monday – the last day of 2012.


Obama said that failing to reach a deal would have a negative impact on financial markets.


“If people start seeing that on January 1st this problem still hasn’t been solved, that we haven’t seen the kind of deficit reduction that we could have had had the Republicans been willing to take the deal that I gave them … then obviously that’s going to have an adverse reaction in the markets,” he said.


RARE SENATE SESSION ON SUNDAY


Obama met with congressional leaders at the White House on Friday and declared himself cautiously optimistic about the chances of an agreement, but he noted in the interview that nothing had materialized since then.


“I was modestly optimistic yesterday, but we don’t yet see an agreement. And now the pressure’s on Congress to produce,” he said.


The Senate is scheduled to hold a rare Sunday session beginning at 1 p.m. EST (1800 GMT), but it was not clear whether the chamber would have fiscal-cliff legislation to act upon.


Obama sketched out what he believed to be the most likely scenarios the end the back-and-forth between both sides. Either the congressional leaders would come up with a deal, or Democrats in the Senate would bring a bill to the floor seeking an up-or-down vote to extend tax cuts for middle income earners.


“And if all else fails, if Republicans do in fact decide to block it, so that taxes on middle class families do in fact go up on January 1st, then we’ll come back with a new Congress on January 4th and the first bill that will be introduced on the floor will be to cut taxes on middle class families,” he said.


Obama chided Republicans for resisting his call for tax rates to go up for the top two percent of U.S. earners despite what he viewed as significant compromises on his part to cut spending and reform expensive social programs for the poor and elderly.


“They say that their biggest priority is making sure that we deal with the deficit in a serious way, but the way they’re behaving is that their only priority is making sure that tax breaks for the wealthiest Americans are protected. That seems to be their only overriding, unifying theme,” Obama said.


“The offers that I’ve made to them have been so fair that a lot of Democrats get mad at me. I mean I offered to make some significant changes to our entitlement programs in order to reduce the deficit,” he said.


(Reporting by Jeff Mason; Editing by David Brunnstrom)


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MSF warns Kenya not to send more refugees to stricken camp






LONDON (Reuters) – Conditions in a camp for Somali refugees in Kenya are deplorable and a government plan to send in thousands more would pose a major risk to health, medical charity Medecins Sans Frontieres (MSF) said on Friday.


Kenya has more than half a million refugees from Somalia, which has lacked an effective central government since the outbreak of civil war in 1991.






A series of bombings, shootings and hand-grenade attacks blamed on Somali militants prompted the government on December 18 to stop registering asylum seekers and refugees in urban areas.


A Kenyan official said more than 100,000 refugees must now head to the remote Dadaab camp in the country’s remote north. Amnesty International said the order breached international law.


Dadaab camp was set up 20 years ago and already houses four times the population it was built for. Hunger and disease outbreaks are common.


MSF says its inhabitants suffer from overcrowding and poor sanitation that recent floods had worsened.


“The assistance provided here in Dadaab is already completely overstretched and is not meeting the current needs,” said Elena Velilla, MSF’s head of mission in Kenya.


In the last month, the number of children admitted to Dadaab’s hospital for severe acute malnutrition has doubled to around 300, MSF said. Sixty-three of those were taken to intensive care this week after developing serious complications.


Most of the sick are also suffering from acute watery diarrhea or severe respiratory tract infections, MSF said.


(Reporting by Kate Kelland; Editing by Tom Pfeiffer)


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‘Frankenfish’ Nears FDA Approval as Debate Heats up






Genetically engineered salmon could make its way onto plates in the new year, but your body won’t notice anything fishy about the filet, experts say.


The Food and Drug Administration has determined genetically engineered salmon won’t threaten the environment, clearing it of all but one final hurdle before it shows up on shelves throughout the nation — and igniting a final 60-day debate on whether it poses health risks before it’s officially approved.






Although it’s been nicknamed “Frankenfish” by critics, health professionals say they aren’t worried the lab-engineered salmon will cause more allergies or other harmful effects than any other breed of fish.


“The hard science part is that we have been creating [animals] using genes and natural selection for years to genetically predict what kinds of food animals, and recreational animals and such we have on our planet,” said Dr. William Schaffner, chairman of preventive medicine at Vanderbilt University Medical Center in Nashville, Tenn.


He cited thoroughbred horses, show dogs and crops as examples of genetically engineered plants and animals dating back centuries.


“When Farmer Jones did it in his cornfield to try to get a better crop, it didn’t bother people,” Schaffner said. “When scientist Jones did the same thing in a much more sophisticated fashion in a lab, that does bother people.”




Superfish: DNA-Altered Salmon Coming to Your Dinner Plate? Watch Video





California’s ‘Frakenfood’ Vote, Legalization of Gay Marriage, Pot Watch Video



A biotech company in Massachusetts called AquaBounty created the AquaAdvantage salmon, which is really an Atlantic salmon with an added Pacific salmon gene to make it grow faster and an added eel gene to make it grow year-round.


The end result is a fish that tastes like an Atlantic salmon but grows twice as fast, making it cheaper to produce and sell. Because the FDA likely won’t require a label that says the salmon was genetically modified, consumers won’t know the difference.


Click here to read about ABC News’ exclusive look at the AquaBounty facility.


Schaffner thinks genetically engineered food is one way to help solve world hunger and, as long as the FDA thoroughly reviews it, there shouldn’t be a problem.


But Rep. Dennis Kucinich, D-Ohio, said he’s been disappointed with FDA decisions on genetically modified food since 1992, when the FDA determined it is equivalent to any other food. He said there’s not enough science to allow AquaAdvantage onto our dinner plates, but the biotech industry has had so much influence in Congress that it’s been impossible to stop.


“Now this latest action by the FDA somehow determined that the salmon is safe — safe for who?” he asked. “Safe for the investors?”


Kucinich has introduced legislation related to genetically modified food and labeling in every Congress since 1997, but it has never passed. He said Monsanto, the $ 2 billion company that produces genetically modified seed and pesticides, is partially to blame because it has so much money and influence.


AquaBounty, the biotech firm that makes AquaAdvantage, contributed less than $ 150,000 toward lobbying Congress over the last three years, according to campaign finance records available on OpenSecrets.org. In contrast, Monsanto spent more than $ 19 million lobbying over the same time frame.


Kucinich said the AquaAdvantage issue is a complex one, and worries about whether the genetically altered fish will hurt naturally occurring wild fish populations by overfeeding because they grow twice as fast as their naturally occurring relatives. However, the most recent FDA finding showed that this is not a concern because the fish are mostly sterile and not expected to escape their man-made farms.


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Poor reading skills tied to risk of teen pregnancy






NEW YORK (Reuters Health) – Seventh grade girls who have trouble reading are more likely to get pregnant in high school than average or above-average readers, according to a new study from Philadelphia.


Researchers found that pattern stuck even after they took into account the girls’ race and poverty in their neighborhoods – both of which are tied to teen pregnancy rates.






“We certainly know that social disadvantages definitely play a part in teen pregnancy risk, and certainly poor educational achievement is one of those factors,” said Dr. Krishna Upadhya, a reproductive health and teen pregnancy researcher from Johns Hopkins Children’s Center in Baltimore.


Poor academic skills may play into how teens see their future economic opportunities and influence the risks they take – even if those aren’t conscious decisions, explained Upadhya, who wasn’t involved in the new research.


Dr. Ian Bennett from the University of Pennsylvania and his colleagues looked up standardized test reading scores for 12,339 seventh grade girls from 92 different Philadelphia public schools and tracked them over the next six years.


During that period, 1,616 of the teenagers had a baby, including 201 that gave birth two or three times.


Hispanic and African American girls were more likely than white girls to get pregnant. But education appeared to play a role, as well.


Among girls who scored below average on their reading tests, 21 percent went on to have a baby as a teenager. That compared to 12 percent who had average scores and five percent of girls who scored above average on the standardized tests.


Once race and poverty were taken into consideration, girls with below-average reading skills were two and a half times more likely to have a baby than average-scoring girls, according to findings published in the journal Contraception.


Birth rates among girls ages 15 through 19 were at a record low in the U.S. in 2011 at 31 births for every 1,000 girls, according to the Centers for Disease Control and Prevention. But that rate is still much higher in minority and poorer girls than in white, well-off ones, researchers noted.


And in general, it’s significantly higher than teen birth rates in other wealthy nations.


Teen pregnancies are a concern because young moms and their babies have more health problems and pregnancy-related complications, and girls who get pregnant are at higher risk of dropping out of school.


Upadhya said the answer to preventing teen pregnancy in less-educated girls isn’t simply to add more sex ed to the curriculum.


“This is really about adolescent health and development more broadly, so it’s really important for us to make sure that kids are in schools and in quality educational programs and that they have opportunities to grow and develop academically and vocationally,” she told Reuters Health.


“That is just as important in preventing teen pregnancy as making sure they know where to get condoms.”


SOURCE: http://bit.ly/TcHB0s Contraception, online December 13, 2012.


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Kenya hospital imprisons new mothers with no money






NAIROBI, Kenya (AP) — The director of the Pumwani Maternity Hospital, located in a hardscrabble neighborhood of downtown Nairobi, freely acknowledges that he detains mothers who can’t pay their bills.


Lazarus Omondi says it’s the only way he can keep his medical center running. Now, a New York-based group filed a lawsuit this month in hopes of forcing Pumwani to stop the practice.






Two mothers who live in a mud-wall and tin-roof slum near the maternity hospital said Pumwani wouldn’t let them leave after delivering their babies. The bills the mothers couldn’t afford were $ 60 and $ 160. Guards with sticks would beat mothers who tried to leave without paying, one of the women said.


Omondi says one solution to the problem would be a national health insurance program.


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Light Therapy Helps Ease Winter Blues






Every October as the clocks are turned back, Jose Balido notices that his mood changes, almost as if his body were going into hibernation.


His limbs are heavy and he has trouble moving around. Simple household chores like loading the dishwasher seem “insurmountable,” he said. But when spring arrives, the lethargy lifts.






“It took me a while to realize what it was,” said Balido, owner of a travel social network site, Tripatini. “I was cranky, short-tempered, depressed, feeling hopeless and having difficulty concentrating.”


Balido, 51, was diagnosed a decade ago with seasonal affective disorder or SAD. The condition affects 62 million Americans, according to Michael Terman, director of the Center for Light Treatment and Biological Rhythms at Columbia University and a leader in the field.


About 5 percent of the population experiences the most severe symptoms of SAD — depression and hopelessness — while another 15 percent have the so-called “winter blues” or “winter doldrums.”


The vast majority never fall into full depression, according to Terman, but “plod through winters with slowness and gloominess that takes effort to hide from others.”


Two decades ago, SAD was identified as a legitimate disorder by the National Institute of Mental Health. Since then, the treatment of choice has been light therapy.


Balido, who lives in Miami, sought help from Terman and now undergoes light therapy. He sits in front of a daylight simulator for a half an hour each morning before 10 a.m.


“Within two or three days, the difference was mind-blowing,” he said.


The standard treatment for SAD is 30 minutes of 10,000-lux, diffused, white fluorescent light, used early in the morning. About half the patients are helped quickly — and when treatment is tailored to a person’s individual wake-sleep cycle, remission can climb to 80 percent, according to Terman.


This year, a utility company in the northern Swedish town of Umea installed ultraviolet lights at 30 bus stops to combat the effects of SAD.


“We wanted to celebrate the fact that all our electricity comes from green sources and we wanted to do this in a way that contributed to the citizens in one way or another,” said Umea Energi marketing chief Anna Norrgard in an email to ABCNews.com.


“As it is very dark where we live this time of year, a lot of us are longing for the daylight,” she said. “A lot of us are also a bit more tired this time of year and I would also say we sleep a little bit more. …We wanted to give the citizens of Umea a little energy boost, to be more alert.”


The town is located about 400 miles north of Stockholm. In December, the sun rises at about 10 a.m. and sets around 2:30 p.m. Some towns north of the Arctic Circle have no daylight for several weeks in the winter.


Geography has a strong influence on the prevalence of SAD symptoms, according to Terman.


“The common wisdom is that it’s worse the farther north you live, because winter days are so much shorter,” he said. “Not so simple.”


Columbia research shows that in North America, the incidence of SAD rises from the southern to the middle states, but levels off and stays bad from about 38 degrees North latitude (near such cities as San Francisco, St. Louis and Washington, D.C.) up through the northernmost states and Canada, according to Terman.


But the problem becomes “more severe” at the western edges of the northern states and provinces.


“This important finding reveals the underlying trigger for relapses into winter depression, since the sun rises an hour more later at the western edge of a zone,” said Terman, whose book, “Chronotherapy,” looks at the phenomenon.


Esther Kane, a clinical counselor from Vancouver, Canada, said her practice is filled with patients as the long days descend on British Columbia.


Seasonal Affective Disorder Hits Hard in Canada


“On the West Coast where we live it’s so rampant, I can’t even tell you how many people have it,” said Kane. “Everyone is feeling it with the gray skies and rain. It’s like nighttime all the time here.”


Doctors there routinely prescribe fish oil and vitamin D, as well as light therapy to balance out the sleep hormone melatonin and “boost” the feel-good hormone serotonin, according to Kane. Many are also on antidepressants.


“A lot of people depend on alcohol and drugs all of a sudden,” she said. “They are stuffing themselves with carbs and their food intake is up. They have depression symptoms — what’s the point of getting out of bed in the morning when they feel no energy and there is dark all over them?”


“Some suffer so bad, they can’t function,” said Kane. “Everyone here who can afford to get away for two weeks in the winter, go to Hawaii.”


Even those who live south of the Mason-Dixon Line in the United States can be affected.


Tina Saratsiotis, who works for a faith-based nonprofit group in Towson, Md., was surprised to develop SAD several years ago.


“I used to be a night person and like the dark. Then something changed,” she said. “By fall when it gets darker and the fatigue and sadness comes and by Christmas, it’s difficult to function.”


“It creeps in slowly — I eat more and have trouble concentrating,” she said. “I am more irritable and weeping, like a prolonged version of PMS. It makes it hard to get things done and to enjoy things.”


Columbia’s Terman said there may be genetic influences in who gets SAD — a vulnerability to depression and to insufficient light exposure.


SAD sufferers say it’s especially hard on their relationships when their winter moods kick in.


“Now, he’s very understanding,” said Saratsiotis, who uses both light therapy and antidepressants to deal with the condition. “But before, when I didn’t feel up to going out, I couldn’t explain not feeling great. People wonder, ‘Why doesn’t she like me?’ and, ‘She’s no fun.’”


But when spring rolls around, so does her old self.


“I love the solstice — thank you, Lord, for the solstice,” she said. “I really need [the medication] now, but I may not in the spring and summer.”


But now, in when the days are their shortest, SAD puts a crimp on the holidays.


“It kills Christmas,” said Saratsiotis. “I sit in the middle of the department store with that particular song about the sleigh bells ringing, and I am sobbing. I burst into tears and think, ‘Just kill that song.’”


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Light Therapy Helps Ease Winter Blues






Every October as the clocks are turned back, Jose Balido notices that his mood changes, almost as if his body were going into hibernation.


His limbs are heavy and he has trouble moving around. Simple household chores like loading the dishwasher seem “insurmountable,” he said. But when spring arrives, the lethargy lifts.






“It took me a while to realize what it was,” said Balido, owner of a travel social network site, Tripatini. “I was cranky, short-tempered, depressed, feeling hopeless and having difficulty concentrating.”


Balido, 51, was diagnosed a decade ago with seasonal affective disorder or SAD. The condition affects 62 million Americans, according to Michael Terman, director of the Center for Light Treatment and Biological Rhythms at Columbia University and a leader in the field.


About 5 percent of the population experiences the most severe symptoms of SAD — depression and hopelessness — while another 15 percent have the so-called “winter blues” or “winter doldrums.”


The vast majority never fall into full depression, according to Terman, but “plod through winters with slowness and gloominess that takes effort to hide from others.”


Two decades ago, SAD was identified as a legitimate disorder by the National Institute of Mental Health. Since then, the treatment of choice has been light therapy.


Balido, who lives in Miami, sought help from Terman and now undergoes light therapy. He sits in front of a daylight simulator for a half an hour each morning before 10 a.m.


“Within two or three days, the difference was mind-blowing,” he said.


The standard treatment for SAD is 30 minutes of 10,000-lux, diffused, white fluorescent light, used early in the morning. About half the patients are helped quickly — and when treatment is tailored to a person’s individual wake-sleep cycle, remission can climb to 80 percent, according to Terman.


This year, a utility company in the northern Swedish town of Umea installed ultraviolet lights at 30 bus stops to combat the effects of SAD.


“We wanted to celebrate the fact that all our electricity comes from green sources and we wanted to do this in a way that contributed to the citizens in one way or another,” said Umea Energi marketing chief Anna Norrgard in an email to ABCNews.com.


“As it is very dark where we live this time of year, a lot of us are longing for the daylight,” she said. “A lot of us are also a bit more tired this time of year and I would also say we sleep a little bit more. …We wanted to give the citizens of Umea a little energy boost, to be more alert.”


The town is located about 400 miles north of Stockholm. In December, the sun rises at about 10 a.m. and sets around 2:30 p.m. Some towns north of the Arctic Circle have no daylight for several weeks in the winter.


Geography has a strong influence on the prevalence of SAD symptoms, according to Terman.


“The common wisdom is that it’s worse the farther north you live, because winter days are so much shorter,” he said. “Not so simple.”


Columbia research shows that in North America, the incidence of SAD rises from the southern to the middle states, but levels off and stays bad from about 38 degrees North latitude (near such cities as San Francisco, St. Louis and Washington, D.C.) up through the northernmost states and Canada, according to Terman.


But the problem becomes “more severe” at the western edges of the northern states and provinces.


“This important finding reveals the underlying trigger for relapses into winter depression, since the sun rises an hour more later at the western edge of a zone,” said Terman, whose book, “Chronotherapy,” looks at the phenomenon.


Esther Kane, a clinical counselor from Vancouver, Canada, said her practice is filled with patients as the long days descend on British Columbia.


Seasonal Affective Disorder Hits Hard in Canada


“On the West Coast where we live it’s so rampant, I can’t even tell you how many people have it,” said Kane. “Everyone is feeling it with the gray skies and rain. It’s like nighttime all the time here.”


Doctors there routinely prescribe fish oil and vitamin D, as well as light therapy to balance out the sleep hormone melatonin and “boost” the feel-good hormone serotonin, according to Kane. Many are also on antidepressants.


“A lot of people depend on alcohol and drugs all of a sudden,” she said. “They are stuffing themselves with carbs and their food intake is up. They have depression symptoms — what’s the point of getting out of bed in the morning when they feel no energy and there is dark all over them?”


“Some suffer so bad, they can’t function,” said Kane. “Everyone here who can afford to get away for two weeks in the winter, go to Hawaii.”


Even those who live south of the Mason-Dixon Line in the United States can be affected.


Tina Saratsiotis, who works for a faith-based nonprofit group in Towson, Md., was surprised to develop SAD several years ago.


“I used to be a night person and like the dark. Then something changed,” she said. “By fall when it gets darker and the fatigue and sadness comes and by Christmas, it’s difficult to function.”


“It creeps in slowly — I eat more and have trouble concentrating,” she said. “I am more irritable and weeping, like a prolonged version of PMS. It makes it hard to get things done and to enjoy things.”


Columbia’s Terman said there may be genetic influences in who gets SAD — a vulnerability to depression and to insufficient light exposure.


SAD sufferers say it’s especially hard on their relationships when their winter moods kick in.


“Now, he’s very understanding,” said Saratsiotis, who uses both light therapy and antidepressants to deal with the condition. “But before, when I didn’t feel up to going out, I couldn’t explain not feeling great. People wonder, ‘Why doesn’t she like me?’ and, ‘She’s no fun.’”


But when spring rolls around, so does her old self.


“I love the solstice — thank you, Lord, for the solstice,” she said. “I really need [the medication] now, but I may not in the spring and summer.”


But now, in when the days are their shortest, SAD puts a crimp on the holidays.


“It kills Christmas,” said Saratsiotis. “I sit in the middle of the department store with that particular song about the sleigh bells ringing, and I am sobbing. I burst into tears and think, ‘Just kill that song.’”


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The Medical Guide to Holiday Movies







Anna Karenina lies febrile on her post-partum bed, her husband, Karenin, and lover, Vronsky, flanking her in sorrow. She repents to each, anticipating her end, and just when the romance soars to its peak, you wonder aloud — why does she have a fever? And, could this really happen?


Luckily, we’ve got Hollywood’s holiday ailments covered. Our unofficial disease guide takes a shot at unraveling the medical mysteries you’ll see woven throughout the biggest hits of the season.








Medical Guide to Holiday Movies


Denzel Washington plays a drug-addicted, alcoholic airline pilot who executes a miracle crash landing but is later blamed for the incident.


ALCOHOLISM


It turns out that drinking and flying is relatively rare. But that wasn’t true in the 1960s. A landmark article on aviation and alcohol found that in 35 percent of all fatal airline accidents in 1963, the pilots had measurable levels of alcohol in their blood. A disproportionate amount of these accidents occurred at night and most occurred within the first half-hour of flight.


So how does alcohol affect flight performance? One scientific article reports that blood alcohol concentrations in the range of 0.03 to 0.05-percent can impair performance of tasks like tracking radio-frequency signals, airport traffic control vectoring, traffic observation and avoidance, and aircraft descent. That’s about the amount present after just one drink for an average size adult.


POST-TRAUMATIC STRESS SYNDROME (PTSD)


According to the book, Aviation Mental Health, pilots may be at risk for PTSD if they’ve ever experienced an aircraft mishap or near mishap. Because of this, the airline industry has a program in place called the Critical Incident Response Program that guides pilots through any potential PTSD inciting events. In addition to this, Federal law requires that all airline employees and their families have access to such counseling programs when faced with significant incidents like aircraft accidents.


When it comes to needing medication however, pilots face a double-edged sword. While counseling services for psychiatric conditions like PTSD are not reportable to the FAA, the use of certain medications is. Pilots are required to report use of any psychotropic medications beyond common antidepressants and refrain from flying until they are medication-free.




Medical Guide to Holiday Movies


Daniel Day-Lewis and Sally Field recreate the spirit of America’s first power couple and highlight the staggering height difference between Abe and Mary Todd.


MARFAN SYNDROME


At 6 feet, 4 inchesl, Abe Lincoln towered nearly 9 inches taller than the average 1860s man. Like a taupe, tailless Na’vi from the movie Avatar, his long legs and spidery fingers intimidated adversaries near and far. But his stately frame was more than just a normal variant. Historians have speculated that Lincoln was afflicted with a rare genetic disorder called Marfan syndrome. The disorder affects connective tissues in the body, causing skeletal abnormalities, and problems with the heart, eyes, and lungs. In addition to being extraordinarily tall, people with Marfan’s are often lanky, with long, slender limbs (dolichostenomelia) and fingers (arachnodactyly).


Some experts argue however that Lincoln instead had a condition called multiple endocrine neoplasia type 2, or MEN2. People with this disorder can also be unusually tall. Either way, his condition would have gone unnamed during his lifetime as Dr. Antoine Marfan, the French pediatrician who first described the condition, didn’t do so until 1896—well after President Lincoln’s untimely death.




Medical Guide to Holiday Movies


Keira Knightly stars in yet another period piece, this time portraying Leo Tolstoy’s beloved, Anna Karenina — a 19th century Russian aristocratic beauty caught in a nasty love triangle.


ENDOMETRITIS


Shortly after giving birth, Karenina experiences a high-grade fever that sends both her lovers to their knees, anticipating the worst. Puerperal fever, or endometritis as it’s now called, was known historically as “the doctor’s plague.” With no concept of germs, doctors often had no reason to wash their hands before attending to births. As such, they often precipitated such post-partum infections, giving thousands of women a simultaneous childbed and deathbed.


Other famous victims include Elizabeth of York, King Henry VIII’s mother, and his third wife, Jane Seymour. It is worth noting that, with the advent of antibiotics and modern-day hygiene, the chances of dying from a post-partum infection today are now incredibly rare.




Medical Guide to Holiday Movies


An all-star cast brings this classic tale of love and loss to the big screen this Christmas Day. And given its historical precedence, we’ll assume we’re not spoiling too much by first announcing Fantine’s death before diving into an explanation of the disease that kills her.


TUBERCULOSIS


Was there ever a more culturally documented medical affliction than consumption, or tuberculosis as it’s known medically? Perhaps not, and that’s why we see so many references to it in popular literature, music and film. Les Miserables is the latest creation to highlight the devastating effects of an infectious disease still commonly seen in third world countries.


TB is a contagious bacterial infection that attacks the lungs and less commonly, other organs. It causes fever, night sweats, weight loss, and sometimes hemetemesis—the coughing up of blood. It’s no wonder that folklore has often associated this disease with vampirism. An article in the American Journal of Physical Anthropology reports that prior to the Industrial Revolution, people interpreted the subsequent deaths of TB patients’ family members as proof that the initial victim was draining them of their lives. In other words, patient zero coughed up blood and therefore, was a vampire.


Today, some countries vaccinate against tuberculosis with a strain of the live, but weakened form of bacteria that infects cows. The vaccine works for only a limited amount of time and its efficacy is limited by geographic region. In the U.S., doctors screen only high risk populations like health care workers and recent immigrants.




Medical Guide to Holiday Movies


Bilbo Baggins returns in this prequel to Lord of the Rings, leading a group of dwarves on a riveting adventure through Middle Earth.


DWARFISM


Is it the hobbits that are really short or the elves that really tall? It’s all relative when it comes to height. If we assume however, that hobbits truly are little people, then it’s safe to say this is a generalized condition that’s associated with upwards of 200 different medical conditions. Either way, the National Institutes of Health defines a dwarf as someone of very short stature — usually under 4’10″ as an adult. Almost 70 percent of all dwarfism cases are due to a condition called achondroplasia, which is a genetic disorder affecting up to 1 in 15,000 people.


Dwarfism itself is not a disease and most little people go on to live healthy, long, and normal lives. Historical prejudice however, often led to their stigmatization as a different kind of being. During the Holocaust, the Nazis went so far as to conduct medical experiments on little people. A shocking example of this was German doctor Josef Mengele’s human zoo — a collection of different looking Jewish prisoners, including a family of dwarves called the Ovitzes.


OBSESSIVE COMPULSIVE DISORDER (OCD)


Greedy little Gollum exhibits the classic signs and symptoms of obsessive compulsive disorder. His obsession with the One Ring is concerning for an all-consuming, socially isolating disorder that nearly 1.5 percent of Americans experience. OCD is an anxiety disorder that causes repetitive, unwanted thoughts or behaviors, often plaguing its victims on a daily basis.


Luckily for patients with OCD, there are many treatment options available. Whether or not Gollum can access these in Middle Earth is an entirely different issue.




Medical Guide to Holiday Movies


Vampires are not real… or are they?


PORPHYRIA


In 1963, an article from the Proceedings of the Royal Society of Medicine entitled, “On Porphyria and the Aetiology of Werwolves” made the case for real life creatures of the night. The paper argued that these so-called beasts were, in fact, humans suffering from congenital prophyria. It references run-ins with these creatures by Pliny, Herodotus, and Virgil, and even offers photographic evidence of the scarring and mutilated human faces that could easily be mistaken for beast.


In 1985, biochemist David Dolphin furthered this association with his widely popularized scientific paper, “Porphyria, Vampires, and Werewolves: The Aetiology of European Metamorphosis Legends.” Not surprisingly, medical experts criticize this and other references for being both fake and promoting of an anti-porphyria stigma.


Porphyria itself is a disorder of the enzymes involved in red blood cell production. It causes neurologic complications and skin problems when affected people are exposed to light. Photosensitivity, blisters, itching, and swelling are just some of the symptoms that no doubt led to a corollary to vampirism. But if sun causes your skin to peel off, doesn’t it make sense that you’d avoid daylight?



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Top 7 Holiday Allergy Triggers







When you wheeze through your fa-la-la’s and your nose rivals Rudolph’s, it’s a little tougher to feel jolly. Although allergies peak in the spring and fall, the holidays may surprise sensitive sufferers with a gift of unexpected triggers, from dusty decorations and potent potpourri to even — say it ain’t so — the Christmas tree.


Here are seven yuletide allergens, and expert tips to help you stay focused on shopping and wrapping, not sneezing and scratching.






How To Keep Your Allergies From Ruining Your Day




Holiday Allergy Triggers


That’s right — the one and only, the centerpiece of all things Christmas, that perfect fir you found hiding in the lot of freshly-cut trees that’s now twinkling with the lights you spent hours untangling — may be to blame for your stuffy nose, watery eyes and rash-y skin.


“Mold is the biggest problem with live Christmas trees,” says Dr. Marilyn Li, an asthma and allergy specialist with the Los Angeles County + University of Southern California Medical Center. “Often, they are cut in advance and kept in humid environments, promoting spore growth.”


Within just two weeks of bringing a tree into your home, indoor mold counts can increase significantly, according to one study.


Other tree-related allergens: The sap contains terpene and other substances that can irritate skin and mucous membranes; and pollen stuck to the tree may be released inside and lead to reactions, adds Dr. Nathanael S. Horne, clinical assistant professor of medicine at NYU school of Medicine and fellow of the American Academy of Allergy, Asthma & Immunology. What about the artificial versions? They could harbor dust and mold from their time in storage, also triggering allergies.


Prevent it: Slip on gloves and wear long sleeves when handling your fresh tree to avoid the sap coming into contact with your skin. Before schlepping your tree inside, give it a good shake (or a blast with a leaf blower) and spray it down with a garden hose (especially the trunk) to help remove some of the pollen and mold, suggests Horne. Then sit the stump in a bucket of water and let the tree dry for few days on a covered porch or in a garage. For an allergen-free fake tree, give it a good wipe-down before decorating with lights and ornaments.


4 Holiday Health Busters




Holiday Allergy Triggers


For eleven months out of the year, all your ornaments, lights, and holiday chotchkes sit stored out of sight, collecting dust and maybe developing mold. When the boxes of red, green, and gold goodies come out, the symphony of sneezing, coughing and nose-blowing commences.


Prevent it: Before decking your halls, mantels, windows and trees, wipe down each item thoroughly; when it’s time to repack, store your holiday trimming in airtight containers, and in a dry spot if possible. Also, go easy on the spray snow — you may love the look of frosted windows, but any aerosolized chemical can cause irritant reactions in the eyes, nose or lungs of a sensitive person, says Horne.




Holiday Allergy Triggers


The fact that she makes “Why aren’t you pregnant yet?” the topic of Christmas dinner is enough to make you break out in hives, but the nuts that she baked into her dessert crust could be to blame, too.


If you have food allergies, the holidays in particular are a ripe time for reactions, simply because you’re around so. much. food. The most common food allergens are milk, eggs, soy, fish, shellfish, peanuts, tree nuts, and wheat.


“Of those, peanuts and tree nuts will most often make it into holiday dishes without people knowing, and have the potential to cause severe reactions,” says Horne.


Prevent it: It’s a good idea to let your holiday host know about your food allergies; it’s important to ask about the ingredients in each dish; and it’s very nice to volunteer to bring something that’s safe for you, and shareable with others. But what’s crucial is to be prepared with an epinephrine auto-injector (Epi Pen), an emergency dose of antihistamine, and an inhaler if you have asthma—just in case, adds Li, director of the USC Breathmobile, a pediatric clinic that travels to schools and provides ongoing asthma and allergy care to children. Learn which foods and recipes are unexpected sources of allergens at FoodAllergy.org and AAAAI.org.


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Holiday Allergy Triggers


You raise a glass to your loved ones, your boss and colleagues, friends and neighbors, and even the strangers sitting next to you at a bar. There’s lots of cheers-ing this time of year, but be mindful of what you’re using to toast. Some people may experience mild wheezing or other symptoms from the sulfites in wine, for example, and certain alcoholic concoctions contain major food allergens.


Prevent it: There aren’t good tests for sulfite sensitivity, but your reaction to dried fruit — high in this sulfur-based preservative — could be an indicator, says Horne. Pay attention if you have asthma, as sulfites can trigger symptoms. Maraschino cherries contain small amounts of sulfites, as well. Stick with organic wine for a sulfite-free sip. Other triggers to be aware of: Tree nuts may be found specialty beers, particularly seasonal ales; milk is in Irish crème and white chocolate liqueurs; and egg whites may be used to add froth to specialty drinks.


Low Calorie Holiday Treats




Holiday Allergy Triggers


This festive plant is a member of the rubber tree family and contains compounds similar to those found in latex, so stay away if you have a latex allergy. Certain groups of people — such as healthcare workers and people with spina bifida who have had numerous surgeries — are more likely to be allergic to latex, says Li, and one study showed that 40 percent of latex-allergic individuals were also allergic to poinsettias.


Prevent it: If you have a latex allergy, keep the iconic plant out of your house—not only can it give you a rash if you touch it, but inhaling the allergen can lead to serious respiratory problems, like shortness of breath and wheezing.


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Holiday Allergy Triggers


Pine-infused potpourri, dessert-scented candles, cinnamon air sprays — while they will make your house smell like Christmas, they can irritate the nose and throats of allergy-sensitive people.


“Candles in particular are an increasingly recognized source of indoor air pollution,” says Horne. “The same is true for air sprays and other types of air fresheners—they can release many different types of noxious compounds, which can generate adverse reactions in sensitive patients.”


Prevent it: If skipping the scents feels Grinch-like, try making your own potpourri with cinnamon sticks and cloves so you know what’s in the mixture, says Horne. And choose candles made of soy or beeswax, suggests Li. There’s not much smell, but you can still enjoy the warm glow. By the way, fireplaces are an absolute no-no for asthmatic patients — the ash and smoke can trigger an attack, so keep the log unlit.


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Holiday Allergy Triggers


Stress doesn’t cause allergies or asthma by itself, but it can hinder your immune system and be a trigger for asthma attacks, says Horne. Chemicals released by the body during stressful times can cause the muscles around your airways to tighten, making it difficult to breathe.


Prevent it: All the deep breathing in the world probably can’t calm the chaos that comes with the season, but what you can do is make sure you take the steps to stay healthy: Stick to your controller medication regimen and get a flu shot, advises Li.


***


More from Prevention:


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South Africa’s Mandela to remain in hospital for Christmas






JOHANNESBURG (Reuters) – Former South African President Nelson Mandela continues to respond to treatment more than two weeks after being taken to hospital in Pretoria and will remain there for Christmas Day, the presidency said on Monday.


The 94-year-old anti-apartheid hero and Nobel Peace laureate has been treated for a lung infection and gallstones after being hospitalized on December 8.






President Jacob Zuma said in a statement that Mandela “will recover from this episode with all our support… We also humbly invite all freedom loving people around the world to pray for him.”


It will be the first Christmas that Mandela has spent away from home since 1989, when he was still in prison. He was jailed for almost three decades for his role in the struggle against white minority rule.


He was released in 1990 and went on to use his prestige to push for reconciliation between whites and blacks as the bedrock of the post-apartheid “Rainbow Nation”.


Mandela was elected South Africa‘s first black president in 1994. He stepped down five years later after one term in office and has been largely removed from public life for the last decade.


(Reporting and writing by Ed Stoddard; Editing by Stella Mapenzauswa and Tom Pfeiffer)


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FDA warns doctors of counterfeit Botox






WASHINGTON (AP) — Federal regulators have warned more than 350 medical practices that Botox they may have received from a Canadian supplier is unapproved and could be counterfeit or unsafe.


The Food and Drug Administration said in a letter sent last month, a letter released publicly last week, that batches of the wrinkle treatment shipped by suppliers owned by pharmacy Canada Drugs have not been approved by the FDA and that the agency cannot assure their effectiveness or their safety.






The FDA said Canada Drugs was previously tied to shipping unapproved and counterfeit cancer drugs.


The agency warned doctors about buying drugs from sources other than licensed U.S. pharmacies. It is the fifth warning the agency has made this year about foreign suppliers providing unapproved drugs.


In February, the agency warned 19 medical practices that they had received a counterfeit version of the cancer drug Avastin. On three more occasions the FDA issued similar warnings about counterfeit Avastin and Altuzan, another brand name for the same drug. The alerts were also primarily targeted at drugs distributed by Canada Drugs.


A request for comment from the drug distributor was not immediately returned.


Drug shortages increased the financial incentives for some pharmacies to provide counterfeit or illegally imported drugs. The drugs subject to warnings have all been injectable treatments typically distributed through medical practices and not directly to patients.


In October, the FDA ordered operators of about 4,100 websites to immediately stop selling unapproved medications to U.S. consumers. The vast majority of those sites were operated by Canada Drugs. The site was still operating Friday.


Genuine Botox is made by Allergan Inc., based in Irvine, Calif. Avastin is made by Roche Holding AG’s Genentech unit.


___


Online:


The FDA’s warning letter, plus a list of doctors who received it: http://1.usa.gov/R7jKiR


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