Novo bets on high-price niche for obesity drug






LONDON (Reuters) – Denmark’s Novo Nordisk is sizing up a high-price niche market for its drug liraglutide as a weight-loss treatment, with the United States the prime opportunity.


The premium-price approach could turn it into a multibillion-dollar-a-year product, the company believes.






Novo is studying the injected drug – already on the market as a treatment for type-2 diabetes under the brand name Victoza – as a therapy for the seriously obese, with pivotal clinical trial results due in the first half of next year.


While some in the industry are sceptical about using so-called GLP-1 diabetes drugs such as liraglutide to fight obesity, Novo’s Chief Science Officer Mads Krogsgaard Thomsen believes the approach can offer cost-effective benefits.


Glucagon-like peptide-1, or GLP-1, drugs work by stimulating insulin release when glucose levels become too high. Their ability to induce weight loss is an added benefit, since type-2 diabetes is linked to obesity.


What is more, the willingness of the U.S. Food and Drug Administration to license new obesity pills from Vivus and Arena Pharmaceuticals last summer shows the door is open to such new medicines, Thomsen said.


“It’s positive. More physicians are now knowledgeable that pharmacotherapy can make a difference and the political establishment in the U.S. now knows that behavior change alone is not enough,” he said in an interview in London.


More than a third of American adults, or some 100 million people, are obese and the figure is rising fast, posing a growing threat to the nation’s health.


Among this population group, liraglutide may help the severely obese, including those with related problems like interrupted breathing during sleep and pre-diabetes, who might otherwise receive stomach surgery.


“We are not going out to treat the 100 million … We see this as solving a problem in a niche of maybe a few million patients,” Thomsen said.


“If you took one million patients and gave them liraglutide at 3.0 milligrams (a day) at the U.S. price that would be a $ 6 billion market.”


When used in diabetes as Victoza, liraglutide is given at daily doses of either 1.2 or 1.8 mg. Novo is betting on a higher dose to produce greater weight-loss in the obese. A key unknown is whether this will produce unacceptable side effects – and Thomsen admits this makes it something of a “joker” in the company’s line-up of new products.


The main adverse effect of Victoza is nausea in some patients, although this is not strong enough in itself to account for the weight loss seen with the drug and Thomsen does not see nausea as a hurdle to regulatory approval.


More worrying, would be any evidence that high-dose liraglutide is linked to pancreatitis.


Given the high safety bar required for a new obesity drug, analysts are currently divided as to whether liraglutide will make it for weight loss – especially given past disappointments with diet drugs such as Sanofi’s Acomplia.


If all goes according to plan, however, Novo aims to file for approval at the end of next year, implying a potential U.S. launch in late 2014 or early 2015 for a product that would add a new string to the bow of the world’s biggest maker of insulin.


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McAfee wants to return to US, ‘normal life’






BACALAR, Mexico (AP) — Software company founder John McAfee said Sunday he wants to return to the United States and “settle down to whatever normal life” he can.


In a live-stream Internet broadcast from the Guatemalan detention center where he is fighting a government order that he be returned to Belize, the 67-year-old said “I simply would like to live comfortably day by day, fish, swim, enjoy my declining years.”






Police in neighboring Belize want to question McAfee in the fatal shooting of a U.S. expatriate who lived near his home on a Belizean island in November.


The creator of the McAfee antivirus program again denied involvement in the killing during the Sunday Internet video hook-up, during which he answered what he said were reporters’ questions.


His comments were sometimes contradictory. McAfee is an acknowledged practical joker who has dabbled in yoga, ultra-light aircraft and the production of herbal medications.


The British-born McAfee first said that returning to the United States “is my only hope now.” But he later added, “I would be happy to go to England, I have dual citizenship.”


He was emphatic that “I cannot ever return to Belize …. there is no hope for my life if I am ever returned to Belize.”


“If I am returned,” he said, “bad things will clearly happen to me.”


He descibed the health problems that had him briefly hospitalized earlier this week after Guatemalan authorities detained him for entering the country illegally. He apparently snuck in across a rural, unguarded spot along the border.


“I did not eat for two days, I drank very little liquids, and for the first time in many years I’ve been smoking almost non-stop,” he said. “I stood up, passed out hit my head on the wall, came to,” though he now said he was feeling better.


McAfee praised the role his 20-year-old Belizean girlfriend, Samantha Vanegas, played in his escape from Belize, where he claims he is being persecuted by corrupt politicians. Authorities in Belize deny that they are persecuting him and have questioned his mental state.


“Sam saved the day many times” during their escape, he said, and suggested he would take her with him to the United States if he is allowed to go there.


He confirmed that journalists from Vice magazine who accompanied him on his escape after weeks of hiding in Belize had unwittingly posted photos with embedded data that revealed his exact location.


“It was an error anyone could make,” he said, noting they were under a lot of pressure at the time.


McAfee has led an eccentric life since he sold his stake in the anti-virus software company named after him in the early 1990s and moved to Belize about three years ago to lower his taxes.


He told The New York Times in 2009 that he had lost all but $ 4 million of his $ 100 million fortune in the U.S. financial crisis. However, a story on the Gizmodo website quoted him as describing that claim as “not very accurate at all.”


McAfee’s Guatemalan attorney, Telesforo Guerra, says that he has filed three separate legal appeals in the hope that his client can stay in Guatemala, where his political asylum request was rejected.


Guerra said he filed an appeal for a judge to make sure McAfee’s physical integrity is protected, an appeal against the asylum denial and a petition with immigration officials to allow his client to stay in this Central American country indefinitely.


The appeals could take several days to resolve, Guerra said. He added that he could still use several other legal resources but wouldn’t give any other details.


Fredy Viana, a spokesman for the Immigration Department, said that before the agency looks into the request to allow McAfee to stay in Guatemala, a judge must first deal with the appeal asking that authorities make sure McAfee’s physical integrity is protected.


“We won’t look into (allowing him to stay) until the other appeal is resolved,” Viana said. “The law gives me 30 days to resolve the issue.”


McAfee went on the run last month after Belizean officials tried to question him about the killing of Gregory Viant Faull, who was shot to death in early November.


McAfee acknowledges that his dogs were bothersome and that Faull had complained about them, but denies killing Faull. Faull’s home was a couple of houses down from McAfee’s compound in Ambergris Caye, off Belize’s Caribbean coast.


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Hug It Out: Public Charter and District Schools Given $25 Million to Get Along






If you need a loan, ask Bill and Melinda Gates. Or better yet, ask one of the seven cities that are splitting a new $ 25 million grant courtesy of the couple’s philanthropic foundation.


The funds are going to promote cross collaboration between charter and district schools, which have previously operated in a strict and contentious independence from one another.






The foundation announced the award this week, and the cities benefiting are Boston, Denver, Hartford (CT), New Orleans, New York City, Philadelphia and Spring Branch (TX).


How did they get so lucky? They’re among a group of 16 communities that signed the Gates-sponsored “District-Charter Collaboration Compacts” pledging for an open-source collaboration between public charter and district public schools.


Communication between these two models is unusual to say the least; they’ve had a long and illustrious history of battling each other over tax dollars, students and even building space.


But when charter schools first opened 20 years ago, their original purpose was to create an experimental educational space which would then share its best methods with public district schools. Instead, the two grew into rivals and critics of each are vehemently opposed to the other.


Among the complaints, charter schools are seen as selfishly siphoning off the most motivated students from the district while upholding a rich-poor educational divide and failing to live up to the promise of a better education. Others say its district schools that are the issue for their unionized teacher complacency and a consistent inability to keep a large margin of students from falling through the cracks.


In truth, neither system is a slam-dunk, and both are experiencing closures nationwide due to underperformance.


The goal of the District-Charter Collaboration Compacts is to restore the original relationship of the two camps, effectively establishing a regular protocol of sharing their best practices, innovations and resources.


Don Shalvey, the deputy director at teh Gates Foundation told The New York Times, “It took Microsoft and Apple 10 years to learn to talk. So it’s not surprising that it took a little bit longer for charters and other public schools. It’s pretty clear there is more common ground than battleground.”


But what will this grand collaboration yield? If all goes according to plan, students from both camps will benefit from new teacher effectiveness practices, college-ready tools and supports, and innovative instructional delivery systems.


According to the Gates Foundation, only one-third of students meet the criteria of college ready by the time they graduate. And most of the kids who don’t are often minority students from lower income areas. By creating collaborative aims with charter and district, kids from all over can have access to a wider swath of teaching frameworks and curriculums. 


Related Stories on TakePart:


• Public Dollars for Private Schools? Voices from the Voucher Debate


• School Vouchers: The Debate Heats Up Across the U.S.


• Howard Fuller: One of the Most Powerful Educators in America



A Bay Area native, Andri Antoniades previously worked as a fashion industry journalist and medical writer.  In addition to reporting the weekend news on TakePart, she volunteers as a webeditor for locally-based nonprofits and works as a freelance feature writer for TimeOutLA.com. Email Andri | @andritweets | TakePart.com


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Springsteen, Lady Gaga join Stones concert in NJ






NEW YORK (AP) — Bruce Springsteen, Lady Gaga and The Black Keys will join the Rolling Stones on Saturday for the final concert marking the band’s 50th anniversary.


The concert will be held at the Prudential Center in Newark, N.J.






The band said Monday the concert will be telecast live on pay-per-view.


The Stones have played in London and New York on their “50 and Counting” tour. They will also play in Newark on Thursday.


The Stones will perform Wednesday at the “12-12-12″ concert at Madison Square Garden in New York City to raise money for victims of Superstorm Sandy.


___


Online:


http://www.rollingstones.com/


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UK chooses doctor as new head of NICE






LONDON (Reuters) – Britain’s health ministry named a former practising doctor, David Haslam, as the preferred candidate to chair the country’s healthcare cost-effectiveness watchdog NICE on Monday.


Haslam will take over as chairman of the renamed National Institute for Health and Care Excellence (NICE) from Michael Rawlins, assuming he passes scrutiny by a committee of MPs.






Rawlins, who has chaired NICE since its creation in 1999, is due to step down in March 2013.


During his time at the helm of the agency, Rawlins has made NICE a powerful force in the pharmaceutical industry with its hard-nosed approach to deciding whether or not pricey new drugs should be used on the state health service.


Haslam, who already leads the NICE Evidence Accreditation Advisory Board, is the immediate past president of the British Medical Association.


NICE will change its official title from the National Institute for Health and Clinical Excellence next year.


(Reporting by Ben Hirschler; editing by Kate Kelland)


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SEAL Team Six member dies in rescue of American doctor




One of the Special Operations troops involved in the raid to free an
American doctor from the Taliban in eastern Afghanistan died of his
wounds today.

A U.S. official confirmed the service member killed in the raid was a member of SEAL Team Six, the same unit that killed Osama bin Laden in May 2011.



"I was deeply saddened to learn that a U.S. service member was killed in the operation, and I also want to extend my condolences to his family, teammates and friends," Defense Secretary Leon Panetta said in a statement released today. "The special operators who conducted this raid knew they were putting their lives on the line to free a fellow American from the enemy's grip. They put the safety of another American ahead of their own, as so many of our brave warriors do every day and every night. In this fallen hero, and all of our special operators, Americans see the highest ideals of citizenship, sacrifice and service upheld. The torch of freedom burns brighter because of them."



President Obama also praised the Special Operations force for their bravery.



"Yesterday, our special operators in Afghanistan rescued an American citizen in a mission that was characteristic of the extraordinary courage, skill and patriotism that our troops show every day," he said today.



"Tragically, we lost one of our special operators in this effort," he said. "Our thoughts and prayers go out to his family, just as we must always honor our troops and military families. He gave his life for his fellow Americans, and he and his teammates remind us once more of the selfless service that allows our nation to stay strong, safe and free."



Dr. Dilip Joseph and two colleagues were kidnapped Dec. 5 by a group of armed men while returning from a visit to a rural medical clinic in eastern Kabul Province, according to a statement from their employer, Colorado Springs-based Morning Star Development. The statement said the three were eventually taken to a mountainous area about 50 miles from the border with Pakistan.



Morning Star's crisis management team in Colorado Springs was in contact with the hostages and their captors almost immediately, the statement said.



On Saturday evening in Afghanistan, two of the three hostages were released. Morning Star did not release their names in order to protect their identities. Dr. Joseph remained in captivity.



Gen. John R. Allen, the commander of U.S. forces in Afghanistan, ordered the mission to rescue Joseph when "intelligence showed that Joseph was in imminent danger of injury or death", according to a military press release.



Morning Star said Joseph was in good condition and will probably return home to Colorado Springs in the next few days.



A Defense Department official told ABC that Joseph can walk, but was beaten up by his captors.



Joseph has worked for Morning Star Development for three years, the organization said, and travels frequently to Afghanistan.



"Morning Star Development does state categorically that we paid no ransom, money or other consideration to the captors or anyone else to secure the release of these hostages," the organization said.

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Hug It Out: Public Charter and District Schools Given $25 Million to Get Along






If you need a loan, ask Bill and Melinda Gates. Or better yet, ask one of the seven cities that are splitting a new $ 25 million grant courtesy of the couple’s philanthropic foundation.


The funds are going to promote cross collaboration between charter and district schools, which have previously operated in a strict and contentious independence from one another.






The foundation announced the award this week, and the cities benefiting are Boston, Denver, Hartford (CT), New Orleans, New York City, Philadelphia and Spring Branch (TX).


How did they get so lucky? They’re among a group of 16 communities that signed the Gates-sponsored “District-Charter Collaboration Compacts” pledging for an open-source collaboration between public charter and district public schools.


Communication between these two models is unusual to say the least; they’ve had a long and illustrious history of battling each other over tax dollars, students and even building space.


But when charter schools first opened 20 years ago, their original purpose was to create an experimental educational space which would then share its best methods with public district schools. Instead, the two grew into rivals and critics of each are vehemently opposed to the other.


Among the complaints, charter schools are seen as selfishly siphoning off the most motivated students from the district while upholding a rich-poor educational divide and failing to live up to the promise of a better education. Others say its district schools that are the issue for their unionized teacher complacency and a consistent inability to keep a large margin of students from falling through the cracks.


In truth, neither system is a slam-dunk, and both are experiencing closures nationwide due to underperformance.


The goal of the District-Charter Collaboration Compacts is to restore the original relationship of the two camps, effectively establishing a regular protocol of sharing their best practices, innovations and resources.


Don Shalvey, the deputy director at teh Gates Foundation told The New York Times, “It took Microsoft and Apple 10 years to learn to talk. So it’s not surprising that it took a little bit longer for charters and other public schools. It’s pretty clear there is more common ground than battleground.”


But what will this grand collaboration yield? If all goes according to plan, students from both camps will benefit from new teacher effectiveness practices, college-ready tools and supports, and innovative instructional delivery systems.


According to the Gates Foundation, only one-third of students meet the criteria of college ready by the time they graduate. And most of the kids who don’t are often minority students from lower income areas. By creating collaborative aims with charter and district, kids from all over can have access to a wider swath of teaching frameworks and curriculums. 


Related Stories on TakePart:


• Public Dollars for Private Schools? Voices from the Voucher Debate


• School Vouchers: The Debate Heats Up Across the U.S.


• Howard Fuller: One of the Most Powerful Educators in America



A Bay Area native, Andri Antoniades previously worked as a fashion industry journalist and medical writer.  In addition to reporting the weekend news on TakePart, she volunteers as a webeditor for locally-based nonprofits and works as a freelance feature writer for TimeOutLA.com. Email Andri | @andritweets | TakePart.com


Linux/Open Source News Headlines – Yahoo! News


Read More..

SEAL Team Six member killed in raid to free kidnapped doctor




One of the Special Operations troops involved in the raid to free an American doctor from the Taliban in eastern Afghanistan died of his wounds today.



A U.S. official confirmed the service member killed in the raid was a member of SEAL Team Six, the same unit that killed Osama bin Laden in May 2011.



"I was deeply saddened to learn that a U.S. service member was killed in the operation, and I also want to extend my condolences to his family, teammates and friends," Defense Secretary Leon Panetta said in a statement released today. "The special operators who conducted this raid knew they were putting their lives on the line to free a fellow American from the enemy's grip. They put the safety of another American ahead of their own, as so many of our brave warriors do every day and every night. In this fallen hero, and all of our special operators, Americans see the highest ideals of citizenship, sacrifice and service upheld. The torch of freedom burns brighter because of them."



President Obama also praised the Special Operations force for their bravery.



"Yesterday, our special operators in Afghanistan rescued an American citizen in a mission that was characteristic of the extraordinary courage, skill and patriotism that our troops show every day," he said today.



"Tragically, we lost one of our special operators in this effort," he said. "Our thoughts and prayers go out to his family, just as we must always honor our troops and military families. He gave his life for his fellow Americans, and he and his teammates remind us once more of the selfless service that allows our nation to stay strong, safe and free."



Dr. Dilip Joseph and two colleagues were kidnapped Dec. 5 by a group of armed men while returning from a visit to a rural medical clinic in eastern Kabul Province, according to a statement from their employer, Colorado Springs-based Morning Star Development. The statement said the three were eventually taken to a mountainous area about 50 miles from the border with Pakistan.



Morning Star's crisis management team in Colorado Springs was in contact with the hostages and their captors almost immediately, the statement said.



On Saturday evening in Afghanistan, two of the three hostages were released. Morning Star did not release their names in order to protect their identities. Dr. Joseph remained in captivity.



Gen. John R. Allen, the commander of U.S. forces in Afghanistan, ordered the mission to rescue Joseph when "intelligence showed that Joseph was in imminent danger of injury or death", according to a military press release.



Morning Star said Joseph was in good condition and will probably return home to Colorado Springs in the next few days.



A Defense Department official told ABC that Joseph can walk, but was beaten up by his captors.



Joseph has worked for Morning Star Development for three years, the organization said, and travels frequently to Afghanistan.



"Morning Star Development does state categorically that we paid no ransom, money or other consideration to the captors or anyone else to secure the release of these hostages," the organization said.

Also Read

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Singer feared dead in Mexican plane crash






MONTERREY, Mexico (AP) — Mexico’s music world mourned Jenni Rivera, the U.S.-born singer presumed killed in a plane crash whose soulful voice and openness about her personal troubles had made her a Mexican-American superstar.


Authorities have not confirmed her death, but Rivera’s relatives in the U.S. say they have few doubts that she was on the Learjet 25 that disintegrated on impact Sunday in rugged territory in Nuevo Leon state in northern Mexico.






“My son Lupillo told me that effectively it was Jenni’s plane that crashed and that everyone on board died,” her father, Pedro Rivera told dozens of reporters gathered in front of his Los Angeles-area home. “I believe my daughter’s body is unrecognizable.”


He said that his son would fly to Monterrey early Monday to identify her presumed remains


Messages of condolence poured in from fellow musicians and celebrities.


Mexican songstress and actress Lucero wrote on her Twitter account: “What terrible news! Rest in peace … My deepest condolences for her family and friends.” Rivera’s colleague on the Mexican show “The Voice of Mexico,” pop star Paulina Rubio, said on her Twitter account: “My friend! Why? There is no consolation. God, please help me!”


Born in Long Beach, California, Rivera was at the peak of her career as perhaps the most successful female singer in grupero, a male-dominated regional style influenced by the norteno, cumbia and ranchero styles.


A 43-year-old mother of five children and grandmother of two, the woman known as the “Diva de la Banda” was known for her frank talk about her struggles to give a good life to her children despite a series of setbacks.


She was recently divorced from her third husband, was once detained at a Mexico City airport with tens of thousands of dollars in cash, and she publicly apologized after her brother assaulted a drunken fan who verbally attacked her in 2011.


Her openness about her personal troubles endeared her to millions in the U.S. and Mexico.


“I am the same as the public, as my fans,” she told The Associated Press in an interview last March.


Rivera sold 15 million records, and recently won two Billboard Mexican Music Awards: Female Artist of the Year and Banda Album of the Year for “Joyas prestadas: Banda.” She was nominated for Latin Grammys in 2002, 2008 and 2011.


Transportation and Communications Minister Gerardo Ruiz Esparza said “everything points toward” the wreckage belonging to the plane carrying Rivera and six other people to Toluca, outside Mexico City, from Monterrey, where the singer had just given a concert.


“There is nothing recognizable, neither material nor human” in the wreckage found in the state of Nuevo Leon, Ruiz Esparza said. The impact was so powerful that the remains of the plane “are scattered over an area of 250 to 300 meters. It is almost unrecognizable.”


A mangled California driver’s license with Rivera’s name and picture was found in the crash site debris.


No cause was given for the plane’s crash, but its wreckage was found near the town of Iturbide in Mexico’s Sierra Madre Oriental, where the terrain is very rough.


The Learjet 25, number N345MC, took off from Monterrey at 3:30 a.m. local time and was reported missing about 10 minutes later. It was registered to Starwood Management of Las Vegas, Nevada, according to FAA records. It was built in 1969 and had a current registration through 2015.


Also believed aboard the plane were her publicist, Arturo Rivera, her lawyer, makeup artist and the flight crew.


Though drug trafficking was the theme of some of her songs, she was not considered a singer of “narco corridos,” or ballads glorifying drug lords like other groups, such as Los Tigres del Norte. She was better known for singing about her troubles in love and disdain for men.


Her parents were Mexicans who had migrated to the United States. Two of her five brothers, Lupillo and Juan Rivera, are also well-known singers of grupero music.


She studied business administration and formally debuted on the music scene in 1995 with the release of her album “Chacalosa”. Due to its success, she recorded two more independent albums, “We Are Rivera” and “Farewell to Selena,” a tribute album to slain singer Selena that helped expand her following.


At the end of the 1990s, Rivera was signed by Sony Music and released two more albums. But widespread success came for her when she joined Fonovisa and released her 2005 album titled “Partier, Rebellious and Daring.”


Besides being a singer, she is also a businesswoman and actress, appearing in the indie film Filly Brown, which was shown at the Sundance Film Festival, as the incarcerated mother of Filly Brown.


She was filming the third season of “I love Jenni,” which followed her as she shared special moments with her children and as she toured through Mexico and the United States. She also has the reality shows: “Jenni Rivera Presents: Chiquis and Raq-C” and her daughter’s “Chiquis ‘n Control.”


In 2009, she was detained at the Mexico City airport when she declared $ 20,000 in cash but was really carrying $ 52,167. She was taken into custody. She said it was an innocent mistake and authorities gave her the benefit of the doubt and released her.


In 2011, her brother Juan assaulted a drunken fan at a popular fair in Guanajuato. In the face of heavy criticism among her fans and on social networks, Rivera publicly apologized for the incident during a concert in Mexico City, telling her fans: “Thank you for accepting me as I am, with my virtues and defects.”


On Saturday night, Rivera had given a concert before thousands of fans in Monterrey. After the concert she gave a press conference during which she spoke of her emotional state following her recent divorce from former Major League Baseball pitcher Esteban Loaiza, who played for teams including the New York Yankees and Los Angeles Dodgers.


“I can’t get caught up in the negative because that destroys you. Perhaps trying to move away from my problems and focus on the positive is the best I can do. I am a woman like any other and ugly things happen to me like any other woman,” she said Saturday night. “The number of times I have fallen down is the number of times I have gotten up.”


Rivera had announced in October that she was divorcing Loaiza after two years of marriage.


There have been several high-profile crashes involving Learjets, known as swift, longer-distance passenger aircraft popular with corporate executives, entertainers and government officials.


A Learjet carrying pro-golfer Payne Stewart and five others crashed in northeastern South Dakota in 1999. Investigators said the plane lost cabin pressure and all on board died after losing consciousness for lack of oxygen. The aircraft flew for several hours on autopilot before running out of fuel and crashing in a corn field.


Former Blink 182 drummer Travis Barker was severely injured in a 2008 Learjet crash in South Carolina that killed four people.


That same year, a Learjet slammed into rush-hour traffic in a posh Mexico City neighborhood, killing Mexico’s No. 2 government official, Interior Secretary Juan Camilo Mourino, and eight others on the plane, plus five people on the ground.


___


Associated Press Writer Galia Garcia-Palafox and Olga R. Rodriguez contributed to this report from Mexico City.


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McAfee wants to return to US, ‘normal life’






BACALAR, Mexico (AP) — Software company founder John McAfee said Sunday he wants to return to the United States and “settle down to whatever normal life” he can.


In a live-stream Internet broadcast from the Guatemalan detention center where he is fighting a government order that he be returned to Belize, the 67-year-old said “I simply would like to live comfortably day by day, fish, swim, enjoy my declining years.”






Police in neighboring Belize want to question McAfee in the fatal shooting of a U.S. expatriate who lived near his home on a Belizean island in November.


The creator of the McAfee antivirus program again denied involvement in the killing during the Sunday Internet video hook-up, during which he answered what he said were reporters’ questions.


His comments were sometimes contradictory. McAfee is an acknowledged practical joker who has dabbled in yoga, ultra-light aircraft and the production of herbal medications.


The British-born McAfee first said that returning to the United States “is my only hope now.” But he later added, “I would be happy to go to England, I have dual citizenship.”


He was emphatic that “I cannot ever return to Belize …. there is no hope for my life if I am ever returned to Belize.”


“If I am returned,” he said, “bad things will clearly happen to me.”


He descibed the health problems that had him briefly hospitalized earlier this week after Guatemalan authorities detained him for entering the country illegally. He apparently snuck in across a rural, unguarded spot along the border.


“I did not eat for two days, I drank very little liquids, and for the first time in many years I’ve been smoking almost non-stop,” he said. “I stood up, passed out hit my head on the wall, came to,” though he now said he was feeling better.


McAfee praised the role his 20-year-old Belizean girlfriend, Samantha Vanegas, played in his escape from Belize, where he claims he is being persecuted by corrupt politicians. Authorities in Belize deny that they are persecuting him and have questioned his mental state.


“Sam saved the day many times” during their escape, he said, and suggested he would take her with him to the United States if he is allowed to go there.


He confirmed that journalists from Vice magazine who accompanied him on his escape after weeks of hiding in Belize had unwittingly posted photos with embedded data that revealed his exact location.


“It was an error anyone could make,” he said, noting they were under a lot of pressure at the time.


McAfee has led an eccentric life since he sold his stake in the anti-virus software company named after him in the early 1990s and moved to Belize about three years ago to lower his taxes.


He told The New York Times in 2009 that he had lost all but $ 4 million of his $ 100 million fortune in the U.S. financial crisis. However, a story on the Gizmodo website quoted him as describing that claim as “not very accurate at all.”


McAfee’s Guatemalan attorney, Telesforo Guerra, says that he has filed three separate legal appeals in the hope that his client can stay in Guatemala, where his political asylum request was rejected.


Guerra said he filed an appeal for a judge to make sure McAfee’s physical integrity is protected, an appeal against the asylum denial and a petition with immigration officials to allow his client to stay in this Central American country indefinitely.


The appeals could take several days to resolve, Guerra said. He added that he could still use several other legal resources but wouldn’t give any other details.


Fredy Viana, a spokesman for the Immigration Department, said that before the agency looks into the request to allow McAfee to stay in Guatemala, a judge must first deal with the appeal asking that authorities make sure McAfee’s physical integrity is protected.


“We won’t look into (allowing him to stay) until the other appeal is resolved,” Viana said. “The law gives me 30 days to resolve the issue.”


McAfee went on the run last month after Belizean officials tried to question him about the killing of Gregory Viant Faull, who was shot to death in early November.


McAfee acknowledges that his dogs were bothersome and that Faull had complained about them, but denies killing Faull. Faull’s home was a couple of houses down from McAfee’s compound in Ambergris Caye, off Belize’s Caribbean coast.


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